Restylane®  Refyne & Defyne


Restylane® Refyne and Restylane® Defyne are fillers specially crafted with XpresHAn Technology™ to soften and smooth the laugh lines that form naturally as the skin ages. Restylane® Refyne and Restylane® Defyne can help restore a full and soft appearance while looking natural and maintaining your same facial expressions.

As skin loses elasticity with age. Signs of again such as the nasolabial folds, which run from your nose to the corners of your mouth and the marionette lines, from the corners of your mouth to the chin, can deepen and become more noticeable throughout the aging process.  Restylane Refyne and Restylane Defyne are specifically formulated hyaluronic acid (HA) dermal fillers made with XpresHAn Technology™ that helps correct lines and signs of aging while still leaving your face with a completely natural look. The unique cross-linking of the gel in Restylane Refyne and Restylane Defyne is also designed to help support your natural expression—for real-life results that maintain natural movement when you're smiling, frowning and even puckering up.




Restylane® Defyne is a flexible gel filler. It is approved for use of moderate to severe deep wrinkles and folds. Defyne is a more dense filler than Restylane® Refyne. Restylane® Defyne can last up to 12 months after treatment and is designed to be flexible to better treat the parts of our face that experience more movement.



Restylane® Refyne is a flexiable gel filler that is often used in the treatment of mild to moderate wrinkles and folds caused by aging. Refyne is a less firm filler than Restylane® Defyne. Restylane® efyne can last up to 12 months after treatment and is designed to be flexible to better treat the parts of our face that experience more movement.



Express yourself flawlessly. Restylane® Refyne and Restylane® Defyne is perfect for when you...


...Show off your beautiful smile


...Or pucker up




...Give a pout


The face and lips are sensitive areas, at Ingrid Trenkle, MD we offer a specially formulated topical numbing cream to help minimize any discomfort during the treatment. If you would like have this numbing, please come in 30 minutes before your scheduled appointment time. This will allow us time to apply and time for the topical cream to have a maximized effect. When you sign in, please let us know you would like to have the numbing cream applied. 

We offer this topical numbing cream for many of our cosmetic treatments, please let us know if you have any concerns or are interested in having topical numbing for your next appointment. Your comfort is of a top priority to us.

Click below to sign up for ASPIRE Galderma Rewards to earn points and save money on your treatments of Restylane Refyne & Defyne